Comparing Apogee Therapeutics (NASDAQ:APGE) and Passage Bio (NASDAQ:PASG)

Apogee Therapeutics (NASDAQ:APGE) and Passage Bio (NASDAQ:PASG) are both medical companies, but which is the better business? We will contrast the two businesses based on the strength of their risk, valuation, analyst recommendations, dividends, institutional ownership, profitability and earnings.

Analyst Ratings

This is a breakdown of current recommendations for Apogee Therapeutics and Passage Bio, as reported by MarketBeat.com.

	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Apogee Therapeutics	0	0	7	0	3.00
Passage Bio	0	0	4	0	3.00

Apogee Therapeutics presently has a consensus target price of $89.71, suggesting a potential upside of 94.02%. Passage Bio has a consensus target price of $7.75, suggesting a potential upside of 1,096.91%. Given Passage Bio’s higher possible upside, analysts clearly believe Passage Bio is more favorable than Apogee Therapeutics.

Profitability

This table compares Apogee Therapeutics and Passage Bio’s net margins, return on equity and return on assets.

	Net Margins	Return on Equity	Return on Assets
Apogee Therapeutics	N/A	-21.81%	-20.94%
Passage Bio	N/A	-72.53%	-52.10%

Earnings & Valuation

This table compares Apogee Therapeutics and Passage Bio”s top-line revenue, earnings per share and valuation.

	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Apogee Therapeutics	N/A	N/A	-$83.99 million	($2.42)	-19.11
Passage Bio	N/A	N/A	-$102.06 million	($1.17)	-0.55

Apogee Therapeutics is trading at a lower price-to-earnings ratio than Passage Bio, indicating that it is currently the more affordable of the two stocks.

Volatility & Risk

Apogee Therapeutics has a beta of 2.33, indicating that its share price is 133% more volatile than the S&P 500. Comparatively, Passage Bio has a beta of 1.43, indicating that its share price is 43% more volatile than the S&P 500.

Institutional and Insider Ownership

79.0% of Apogee Therapeutics shares are owned by institutional investors. Comparatively, 53.5% of Passage Bio shares are owned by institutional investors. 36.1% of Apogee Therapeutics shares are owned by company insiders. Comparatively, 4.3% of Passage Bio shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summary

Apogee Therapeutics beats Passage Bio on 7 of the 10 factors compared between the two stocks.

About Apogee Therapeutics

Apogee Therapeutics, Inc., through its subsidiary, operates as a biotechnology company that develops biologics for the treatment of atopic dermatitis (AD), asthma, chronic obstructive pulmonary disease (COPD), and related inflammatory and immunology indications. The company primarily develops APG777, a subcutaneous (SQ) extended half-life monoclonal antibody (mAb) for AD; and APG808, an SQ extended half-life mAb for COPD. Its earlier-stage programs comprise APG990, an SQ extended half-life mAb for the treatment of AD; and APG222, an extended half-life SQ antibodies for AD. Apogee Therapeutics, Inc. was incorporated in 2022 and is headquartered in Waltham, Massachusetts.

About Passage Bio

Passage Bio, Inc., a genetic medicines company, develops gene therapies for central nervous system diseases. It develops PBGM01, a functional GLB1 gene encoding ß-galactosidase for infantile GM1; PBFT02, a functional granulin (GRN) and gene encoding progranulin (PGRN) for the treatment of FTD caused by progranulin deficiency; and PBKR03, a functional GALC gene encoding the hydrolytic enzyme galactosylceramidase for infantile Krabbe disease. The company develops PBML04 for the treatment of metachromatic leukodystrophy; PBAL05 for the treatment of amyotrophic lateral sclerosis; and other program for huntington's disease. It has a strategic research collaboration with the Trustees of the University of Pennsylvania's Gene Therapy Program; and collaboration agreement, and a development services and clinical supply agreement with Catalent Maryland, Inc. Passage Bio, Inc. was incorporated in 2017 and is headquartered in Philadelphia, Pennsylvania.